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Product Name | Recombinant Escherichia coli Cytolethal distending toxin subunit B (cdtB) |
Description | Purity > 90% as determined by SDS-PAGE. MW: 47.4kDa. Full Length of Mature Protein: 19-269aa. N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Escherichia coli. Part of the tripartite complex that is required for the CDT activity. CdtB exhibits a DNA-nicking endonuclease activity, and very probably causes DNA damage in intoxicated cells. This damage induces G2/M cell cycle arrest, chromatin fragmentation, cell distention and nucleus enlargement. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Deoxyribonuclease CdtB (EC:3.1.-.-) |
Gene, Accession, CAS # | cdtB, UniProt: Q46669 |
Catalog # | RPC20440 |
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Order / More Info | Recombinant Escherichia coli Cytolethal distending toxin subunit B (cdtB) from BIOMATIK |
Product Specific References | n/a |
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