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| Product Name | Recombinant Human Interleukin-36 alpha protein (IL36A) (Active) |
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| Description | Purity > 95% as determined by SDS-PAGE. MW: 15.9kDa. Full Length of Mature Protein: 16-155aa. tag-Free. Homo sapiens (Human). FGF acidic, also known as ECGF, FGF-1and HBGF-1, is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. It is a mitogenic peptide that is produced by multiple cell types and stimulates the proliferation of cells of mesodermal, ectodermal, and endodermal origin. Its association with heparan sulfate is a prerequisite for activation of FGF receptors. Internalized FGF acidic migrates to the nucleus where it is phosphorylated by nuclear PKC delta, exported to the cytosol, dephosphorylated, and degraded. Intracellular FGF acidic inhibits p53 activity and proapoptotic signaling. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Fibroblast Growth Factor 1; FGF-1; Acidic Fibroblast Growth Factor; aFGF; Endothelial Cell Growth Factor; ECGFHeparin-Binding Growth Factor 1; HBGF-1; FGF1; FGFA |
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| Gene, Accession, CAS # | FGF1, UniProt: P05230 |
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| Catalog # | RPC26822 |
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| Order / More Info | Recombinant Human Interleukin-36 alpha protein (IL36A) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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