产品名称 ASK1 Antibody from INVITROGEN ANTIBODIES
产品货号 PA5-20201
产品价格 现货询价,电话:010-67529703
产品规格 100 ug
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityASK1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpurified
Size100 ug
Concentrationn/a
ApplicationsWestern Blot: 1-2 µg/mL
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DescriptionASK1 Polyclonal Antibody. Mitogen-activated protein (MAP) kinase cascades are activated in response to various extracellular stimuli, including cytokines, growth factors and environmental stresses. A novel MAP kinase kinase kinase (MAPKKK) was identified and designated ASK1 (for apoptosis signal-regulating kinase 1) and MAPKKK5. ASK1 activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activates c-Jun N-terminal kinase (JNK) and p38 MAP kinase, respectively. ASK1/MAPKKK5 is activated by TNFR and Fas through the interaction with members of the TRAF family and Fas-associated protein Daxx. Overexpression of ASK1 induced apoptotic cell death and a catalytically inactive form of ASK1 inhibited TNF-a-induced apoptosis. ASK1 is
Immunogenn/a
Other Namesn/a
Gene, Accession #Entrez: 26408, 4217; Uniprot: O35099, Q99683
Catalog #PA5-20201
Price
Order / More InfoASK1 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料