产品名称 Phospho-ASK1 (Ser83) Antibody from INVITROGEN ANTIBODIES
产品货号 MA5-28020
产品价格 现货询价,电话:010-67529703
产品规格 200 µl
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityPhospho-ASK1 (Ser83)
CloneAsk1S83-G4
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
IsotypeIgG1, kappa
Formatpurified
Size200 µl
Concentrationn/a
ApplicationsFlow Cytometry: 0.1-1.0 µg/mL, Western Blot: 0.1-1.0 µg/mL
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DescriptionPhospho-ASK1 (Ser83) Monoclonal Antibody (Ask1S83-G4). Mitogen-activated protein (MAP) kinase cascades are activated in response to various extracellular stimuli, including cytokines, growth factors and environmental stresses. A novel MAP kinase (MAPKKK) was identified and designated ASK1 (for apoptosis signal-regulating kinase 1) and MAPKKK5. ASK1 activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activates c-Jun N-terminal kinase (JNK) and p38 MAP kinase, respectively. ASK1/MAPKKK5 is activated by TNFR and Fas through the interaction with members of the TRAF family and Fas-associated protein Daxx. Overexpression of ASK1 induced apoptotic cell death and a catalytically inactive form of ASK1 inhibited TNF-a-induced apo
Immunogenn/a
Other Namesn/a
Gene, Accession #Entrez: 26408, 365057, 4217; Uniprot: O35099, Q99683
Catalog #MA5-28020
Price
Order / More InfoPhospho-ASK1 (Ser83) Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
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