产品名称 RANK Antibody from INVITROGEN ANTIBODIES
产品货号 MA1-41048
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityRANK
Clone64C1385.1
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1, lambda
Formatpurified
Size100 µg
Concentrationn/a
ApplicationsFlow Cytometry: 5 µg/1x10^6 cells, Immunoprecipitation: 1-2 µg/mL, Western Blot: 1-2 µg/mL
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DescriptionRANK Monoclonal Antibody (64C1385.1). Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Receptor activator of NF-kB (RANK) is a recently cloned member of the TNFR superfamily with no significant homology to other members of this family. RANK ligand (RANKL/TRANCE/ OPGL) binds to RANK on dendritic cells, upregulates the expression of anti-apoptotic protein BcL-XL suggesting a role in dendritic cell survival. The cytoplasmic domain of RANK interacts with TRAF2, TRAF5 and TRAF6. Overexpression of RANK activates NF-kB a
Immunogenn/a
Other NamesFEO, LOH18CR1, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, TRANCER, TNFRSF11A
Gene, Accession #Entrez: 21934, 8792; Uniprot: O35305, Q9Y6Q6
Catalog #MA1-41048
Price
Order / More InfoRANK Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料