产品名称 RANK Antibody from INVITROGEN ANTIBODIES
产品货号 MA1-41015
产品价格 现货询价,电话:010-67529703
产品规格 100 µl
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityRANK
Clone9A725
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1, kappa
Formatphycoerythrin (PE) conjugate
Size100 µl
Concentrationn/a
ApplicationsFlow Cytometry: 0.625 µg/1x10^6 cells
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionRANK Monoclonal Antibody (9A725), PE. Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Receptor activator of NF-kB (RANK) is a recently cloned member of the TNFR superfamily with no significant homology to other members of this family. RANK ligand (RANKL/TRANCE/ OPGL) binds to RANK on dendritic cells, upregulates the expression of anti-apoptotic protein BcL-XL suggesting a role in dendritic cell survival. The cytoplasmic domain of RANK interacts with TRAF2, TRAF5 and TRAF6. Overexpression of RANK activates NF-kB a
Immunogenn/a
Other NamesFEO, LOH18CR1, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, TRANCER, TNFRSF11A
Gene, Accession #Entrez: 21934, 498206, 8792; Uniprot: O35305, Q9Y6Q6
Catalog #MA1-41015
Price
Order / More InfoRANK Antibody from INVITROGEN ANTIBODIES
Product Specific ReferencesPubMed: 22531921, 26329493
产品资料