| 产品详情 |
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| Antigenic Specificity | TLR4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TLR4 Polyclonal Antibody. TLR4, a type I membrane protein that belongs to the Toll-like receptor family, cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). It acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response TLR4 Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, LY96 and TLR. TLR4 binds to LY96 via the extracellular domain, and to MyD88 and TIRAP via their respective TIR domains. The protein contains 19 leucine-rich (LRR) repeats, and It is highly expressed in heart, spleen, lung and muscle. Lower levels are found in liver and kidney. Interstrain analyses reveal that TLR |
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| Immunogen | n/a |
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| Other Names | Toll-like Receptor 4, ARMD10, TLR-4, TOLL, hToll, homolog of Drosophila toll |
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| Gene, Accession # | Entrez: 21898; Uniprot: Q9QUK6 |
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| Catalog # | PA5-11597 |
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| Price | |
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| Order / More Info | TLR4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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