产品详情 |
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Antigenic Specificity | NGFR |
Clone | MC192 |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | ELISA: 5-15 µg/mL, Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent, Immunohistochemistry (PFA fixed): 5-15 µg/mL, Western Blot: 5-15 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NGFR Monoclonal Antibody (MC192). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Homodimer; disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with NGFRAP1/BEX3. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1. |
Immunogen | n/a |
Other Names | TNR16, low-affinity nerve growth factor receptor, NGF receptor, Gp80-LNGFR, p75 ICD, low affinity neurotrophin receptor p75NTR, Tnfrsf16, Ngfr, p75, L, p75, p-75 |
Gene, Accession # | Entrez: 24596; Uniprot: P07174 |
Catalog # | OSM00019A |
Price | |
Order / More Info | NGFR Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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