产品名称 IL-33 Antibody from INVITROGEN ANTIBODIES
产品货号 PA5-20397
产品价格 现货询价,电话:010-67529703
产品规格 100 ug
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityIL-33
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size100 ug
Concentrationn/a
ApplicationsImmunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 20 µg/mL, Western Blot: 1-2 µg/mL
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DescriptionIL-33 Polyclonal Antibody. IL-33 (Interleukin-33) is a 270 amino acid, highly divergent protein belonging to the IL-1 family with an IL-1-like C-terminal domain. IL-33 is a dual function protein that may function both as a proinflammatory cytokine and an intracellular nuclear factor with transcriptional regulatory properties. IL-33 binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6. IL-33 activates NF-kappaB and MAP kinases, and drives production of TH2-associated cytokines from in vitro polarized TH2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs. IL-33 is proteolytically converted to a mature form by CASP1 and
Immunogenn/a
Other Namesn/a
Gene, Accession #Entrez: 90865; Uniprot: O95760
Catalog #PA5-20397
Price
Order / More InfoIL-33 Antibody from INVITROGEN ANTIBODIES
Product Specific ReferencesPubMed: 26808348
产品资料