| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | IL-33 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, nonhuman primate |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 ug |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot: 0.5-2 µg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | IL-33 Polyclonal Antibody. IL-33 (Interleukin-33) is a 270 amino acid, highly divergent protein belonging to the IL-1 family with an IL-1-like C-terminal domain. IL-33 is a dual function protein that may function both as a proinflammatory cytokine and an intracellular nuclear factor with transcriptional regulatory properties. IL-33 binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6. IL-33 activates NF-kappaB and MAP kinases, and drives production of TH2-associated cytokines from in vitro polarized TH2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs. IL-33 is proteolytically converted to a mature form by CASP1 and |
|---|
| Immunogen | n/a |
|---|
| Other Names | C9orf26, DVS27, IL1F11, NF-HEV, NFEHEV, RP11-575C20.2, DVS27-related protein, IL-1F11, IL-33, interleukin-1 family member 11, interleukin-33, nuclear factor for high endothelial venules, nuclear factor from high endothelial venules |
|---|
| Gene, Accession # | Entrez: 90865; Uniprot: O95760 |
|---|
| Catalog # | PA5-23150 |
|---|
| Price | |
|---|
| Order / More Info | IL-33 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|