| 产品详情 |
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| Antigenic Specificity | IL-33 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | ELISA: 0.1-0.4 µg/mL (Detection), 0.2-0.8 µg/mL (Capture), Flow Cytometry: 2.5 µg/1x10^6 cells, Immunocytochemistry: 5-15 µg/mL, Immunofluorescence: 5-15 µg/mL, Immunohistochemistry (Frozen): 5-15 µg/mL, Neutralization: 10-50 ng/mL, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | IL-33 Polyclonal Antibody. IL-33 (Interleukin-33) is a 270 amino acid, highly divergent protein belonging to the IL-1 family with an IL-1-like C-terminal domain. IL-33 is a dual function protein that may function both as a proinflammatory cytokine and an intracellular nuclear factor with transcriptional regulatory properties. IL-33 binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6. IL-33 activates NF-kappaB and MAP kinases, and drives production of TH2-associated cytokines from in vitro polarized TH2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs. IL-33 is proteolytically converted to a mature form by CASP1 and |
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| Immunogen | n/a |
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| Other Names | C9orf26, DVS27, IL1F11, NF-HEV, NFEHEV, RP11-575C20.2, DVS27-related protein, IL-1F11, interleukin-1 family member 11, interleukin-33, nuclear factor for high endothelial venules, nuclear factor from high endothelial venules |
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| Gene, Accession # | Entrez: 77125; Uniprot: Q8BVZ5 |
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| Catalog # | PA5-47007 |
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| Price | |
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| Order / More Info | IL-33 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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