产品名称 IL-33 Antibody from INVITROGEN ANTIBODIES
产品货号 PA5-79499
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
Edit&nbsp
Antigenic SpecificityIL-33
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formatpurified
Size100 µg
Concentrationlyophilized
ApplicationsELISA: Assay-dependent, Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 0.5 µg/mL
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionIL-33 Polyclonal Antibody. IL-33 (Interleukin-33) is a 270 amino acid, highly divergent protein belonging to the IL-1 family with an IL-1-like C-terminal domain. IL-33 is a dual function protein that may function both as a proinflammatory cytokine and an intracellular nuclear factor with transcriptional regulatory properties. IL-33 binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6. IL-33 activates NF-kappaB and MAP kinases, and drives production of TH2-associated cytokines from in vitro polarized TH2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs. IL-33 is proteolytically converted to a mature form by CASP1 and
Immunogenn/a
Other NamesInterleukin-33, IL-33, Il33
Gene, Accession #Entrez: 361749, 77125; Uniprot: Q66H70, Q8BVZ5
Catalog #PA5-79499
Price
Order / More InfoIL-33 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料