| 产品详情 |
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| Antigenic Specificity | IL-33R (ST2) |
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| Clone | RMST2-2 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, kappa |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.25 µg/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | IL-33R (ST2) Monoclonal Antibody (RMST2-2), APC, eBioscience™. ST2 is a member of the interleukin 1 receptor family. Studies of ST2 in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. ST2 belongs to the interleukin-1 receptor family with three Ig-like C2-type (immunoglobulin-like) domains and a TIR domain. ST2 is a receptor for interleukin-33 (IL-33) which upon stimulation recruits the signaling molecules MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Reports also suggest its possible role in helper T-cell function as well as in cell growth. Three isoforms of ST2 have been reported where |
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| Immunogen | n/a |
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| Other Names | DER4, Fit-1, Ly84, ST2L, St2, St2-rs1, T1, T1/ST2 |
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| Gene, Accession # | Entrez: 17082; Uniprot: P14719 |
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| Catalog # | 17-9335-80 |
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| Price | |
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| Order / More Info | IL-33R (ST2) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 27582256, 28742815, 29045903, 29440650, 29535723 |
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