| 产品详情 |
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| Antigenic Specificity | IRAK4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | IRAK4 Polyclonal Antibody. The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). IL-1 receptor-associated kinases (IRAKs) are important mediators in the signal transduction of Toll/IL-1 receptor (TIR) family members (2). The cytoplasmic domains of TIR proteins interact with the adapter protein, MyD88. MyD88 then recruits IRAKs (IRAK-1, -2, and M), which in turn interact with other adapter molecules, such as TRAF6 to activate NF-kB and MAPK pathways. Recently, a new member of this family, IRAK |
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| Immunogen | n/a |
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| Other Names | IPD1, NY-REN-64, REN64 |
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| Gene, Accession # | Entrez: 266632, 300177, 51135; Uniprot: Q8R4K2, Q9NWZ3 |
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| Catalog # | PA1-41054 |
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| Price | |
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| Order / More Info | IRAK4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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