产品名称 Phospho-TAK1 (Thr187) Antibody from INVITROGEN ANTIBODIES
产品货号 PA5-12757
产品价格 现货询价,电话:010-67529703
产品规格 400 µL
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityPhospho-TAK1 (Thr187)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size400 µL
Concentrationn/a
ApplicationsDot blot: 1:500
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPhospho-TAK1 (Thr187) Polyclonal Antibody. TAK1 (also known as MAP3K7), a part of the serine/threonine kinase family, is a versatile protein with many signaling functions. Originally identified as a TGF- beta-activated kinase, TAK1 interacts with TGF- beta-receptor and TRAF6 to modulate TGF- beta activation of JNK and p38. It has additional roles in activation of p38 and JNK through Wnt, BMP, and activin signaling pathways as well in response to thyroid hormone, osmotic stress, endothelin, and ephrine. Through activation of von Hippel-Lindau tumor suppressor expression, TAK1 represses PDGF-B, integrin beta1 and integrin beta5, promoting proper wound healing. TAK1 also plays an essential role in IKK activation in numerous signaling pathways
Immunogenn/a
Other NamesMitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1; TAK1
Gene, Accession #Entrez: 6885; Uniprot: O43318
Catalog #PA5-12757
Price
Order / More InfoPhospho-TAK1 (Thr187) Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料