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| Antigenic Specificity | IL-33R (ST2) |
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| Clone | hIL33Rcap |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | PerCP-eFluor 710 conjugate |
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| Size | 100 Tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 5 µL (0.125 µg)/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | IL-33R (ST2) Monoclonal Antibody (hIL33Rcap), PerCP-eFluor 710, eBioscience™. IL-33R, also known as ST2, is a receptor for IL-33. It is a member of the IL-1 receptor family of innate receptors. Its extracellular domain consists of 3 Ig-like domains that directly interact with its co-receptor IL-1RAcP, and the ligand alarmin, IL-33. IL-33 ligation results in the association of IL-33R complex with its adaptor proteins MyD88, IRAK1, IRAK4 and TRAF6, and activation of the NF-kB, and MAPK pathways. This, in turn, instigates the release of chemokines and cytokines such as IL-5, IL-6, IL-8, and IL-13. Two most common isoforms of IL-33R that result from alternative splicing are ST2L - the membrane bound form, and ST2S - the soluble form. The |
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| Immunogen | n/a |
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| Other Names | IL1RL1, DER4, FIT1, T1 |
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| Gene, Accession # | Entrez: 9173; Uniprot: Q01638 |
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| Catalog # | 46-9338-42 |
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| Price | |
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| Order / More Info | IL-33R (ST2) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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