产品名称 CD254 (RANK Ligand) Antibody from INVITROGEN ANTIBODIES
产品货号 12-5952-81
产品价格 现货询价,电话:010-67529703
产品规格 50 µg
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityCD254 (RANK Ligand)
CloneIK22/5
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a, kappa
Formatphycoerythrin (PE) conjugate
Size50 µg
Concentrationn/a
ApplicationsFlow Cytometry: 0.25 µg/test
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionCD254 (RANK Ligand) Monoclonal Antibody (IK22/5), PE, eBioscience™. This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in
Immunogenn/a
Other NamesRP11-86N24.2, CD254, ODF, OPGL, OPTB2, RANKL, TRANCE, hRANKL2, sOdf, TNF-related activation-induced cytokine, TNFSF11, TRANCE
Gene, Accession #Entrez: 21943; Uniprot: O35235
Catalog #12-5952-81
Price
Order / More InfoCD254 (RANK Ligand) Antibody from INVITROGEN ANTIBODIES
Product Specific ReferencesPubMed: 17998311, 18382763, 19380791, 22714558, 27340353
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