| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD254 (RANK Ligand) |
|---|
| Clone | MIH24 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG2b, kappa |
|---|
| Format | phycoerythrin (PE) conjugate |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 0.125 µg/test |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD254 (RANK Ligand) Monoclonal Antibody (MIH24), PE, eBioscience™. This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in t |
|---|
| Immunogen | n/a |
|---|
| Other Names | RP11-86N24.2, CD254, ODF, OPGL, OPTB2, RANKL, TRANCE, hRANKL2, sOdf, TNF-related activation-induced cytokine, TNFSF11, TRANCE |
|---|
| Gene, Accession # | Entrez: 8600; Uniprot: O14788 |
|---|
| Catalog # | 12-6619-82 |
|---|
| Price | |
|---|
| Order / More Info | CD254 (RANK Ligand) Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 20615964, 22952578 |
|---|
| 产品资料 |
|
|