| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD254 (RANK Ligand) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Goat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µg |
|---|
| Concentration | lyophilized |
|---|
| Applications | ELISA: 0.1-0.4 µg/mL (Detection), 0.2-0.8 µg/mL (Capture), Immunohistochemistry: 5-15 µg/mL, Neutralization: 0.02-0.06 µg/mL, Western Blot: 0.1 µg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD254 (RANK Ligand) Polyclonal Antibody. This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. |
|---|
| Immunogen | n/a |
|---|
| Other Names | RP11-86N24.2, CD254, ODF, OPGL, OPTB2, RANKL, TRANCE, hRANKL2, sOdf, TNF-related activation-induced cytokine, TNFSF11, TRANCE |
|---|
| Gene, Accession # | Entrez: 21943; Uniprot: O35235 |
|---|
| Catalog # | PA5-47641 |
|---|
| Price | |
|---|
| Order / More Info | CD254 (RANK Ligand) Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|