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| Product Name | AKR1C3, 1-323aa, Human, His tag, E.coli (Bioactivity Validated) |
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| Description | Purity: > 95% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol . AKR1C3, also known as PGFS, is a member of the aldo-keto reductase superfamily which catalyzes the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9 alpha, 11 beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and differentiation. Recombinant human AKR1C3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | Enzyme activity |
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| Other Names | Aldo-keto reductase family 1 member C3, Aldo-keto reductase family 1, member C3, DD3, DDX, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5, KIAA0119, Aldo-keto reductase family 1, member C3 17 beta HSD 5, AKR1 C3, Chlordecone reductase, 17 beta hydroxysteroid dehydrogenase type 5, Aldo keto reductase family 1 member C3, DDH1, HAKRe, HSD17B5, PGFS, Prostaglandin F synthase, |
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| Gene, Accession, CAS # | NP 003730 |
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| Catalog # | ATGP0270 |
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| Order / More Info | AKR1C3, 1-323aa, Human, His tag, E.coli (Bioactivity Validated) from ATGen |
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| Product Specific References | n/a |
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