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Product Name | Aldo-keto reductase family 1 member C3 isoform 1, 1-323aa, Human, E.coli (Bioactivity Validated) |
Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.5) containing 0.1M NaCl, 10% glycerol, 1mM DTT . AKR1C3 also known as Aldo-keto reductase family 1 member C3 isoform 1, is a member of the aldo-keto reductase superfamily which catalyzes the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9 alpha, 11 beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and differentiation. Recombinant human AKR1C3 protein was expressed in E.coli and purified by using conventional chromatography techniques. |
Size | 50ug, 10ug, |
Concentration | n/a |
Applications | Enzyme activity |
Other Names | DD3, DDX, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5, PGFS |
Gene, Accession, CAS # | NP 003730 |
Catalog # | ATGP3276 |
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Order / More Info | Aldo-keto reductase family 1 member C3 isoform 1, 1-323aa, Human, E.coli (Bioactivity Validated) from ATGen |
Product Specific References | n/a |
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