| 产品详情 |
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| Antigenic Specificity | VISTA |
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| Clone | B7H5DS8 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 100 Tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 5 µL (0.25 µg)/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | VISTA Monoclonal Antibody (B7H5DS8), APC, eBioscience™. VISTA (V-domain Ig containing suppressor of T-cell activation), also known as B7-H5 or PD-H1, is a product of the VSIR gene. Although VISTA bears sequence homology to PD-L1 it has a different expression pattern. In both mouse and humans VISTA is expressed predominantly on hematopoietic cells with the highest densities on CD11b+ myeloid cells, and somewhat lower levels on CD4 and CD8 T cells. VISTA expressed by antigen presenting cells has been shown to directly suppress proliferation and cytokine production of CD4 and CD8 T cells, making it a target for cancer immunotherapy. Mice deficient in VISTA are viable and have elevated frequencies of activated T cells but do not spontaneo |
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| Immunogen | n/a |
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| Other Names | B7-H5, PD-H1, Gi24, Dies1, SISP1, C10orf54 |
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| Gene, Accession # | Entrez: 64115; Uniprot: Q9H7M9 |
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| Catalog # | 17-1088-42 |
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| Price | |
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| Order / More Info | VISTA Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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