产品详情 |
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Antigenic Specificity | CD273 (B7-DC) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | Immunohistochemistry: 5-15 µg/mL, Neutralization: Assay-Dependent, Western Blot: 0.1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD273 (B7-DC) Polyclonal Antibody. Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist, this antibody is specific to the largest isoform. PD |
Immunogen | n/a |
Other Names | PD-L2, B7DC, Btdc, PDCD1L2, PDL2, bA574F11.2, B7 dendritic cell molecule, B7-DC, PD-1 ligand 2, PD-1-ligand 2, PDCD1 ligand 2, butyrophilin B7-DC, programmed death ligand 2 |
Gene, Accession # | Entrez: 80380; Uniprot: Q9BQ51 |
Catalog # | PA5-47098 |
Price | |
Order / More Info | CD273 (B7-DC) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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