产品名称 AP2M1 Antibody from INVITROGEN ANTIBODIES
产品货号 MA5-25571
产品价格 现货询价,电话:010-67529703
产品规格 100 µl
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityAP2M1
CloneOTI1B11
Host SpeciesMouse
Reactive Specieshuman, nonhuman primate
IsotypeIgG2a
Formatpurified
Size100 µl
Concentrationn/a
ApplicationsFlow Cytometry: 1:100, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Western Blot: 1:500-1:2000
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DescriptionAP2M1 Monoclonal Antibody (OTI1B11). The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP
Immunogenn/a
Other NamesAP50, CLAPM1, mu2; AP-2 complex subunit mu; AP-2 mu 2 chain; AP-2 mu chain; HA2 50 kDA subunit; adapter-related protein complex 2 mu subunit; adaptin-mu2; adaptor protein complex AP-2 subunit mu; clathrin adaptor complex AP2, mu subunit; clathrin assembly protein complex 2 medium chain; clathrin coat adaptor protein AP50; clathrin coat assembly protein AP50; clathrin coat-associated protein AP50; clathrin-associated/assembly/adaptor protein, medium 1; plasma membrane adaptor AP-2 50 kDa protein;
Gene, Accession #Entrez: 102131193, 1173; Uniprot: Q4R706, Q96CW1
Catalog #MA5-25571
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Order / More InfoAP2M1 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
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