产品详情 |
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Antigenic Specificity | IL-17F |
Clone | 4H450 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Western Blot: 0.2-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-17F Monoclonal Antibody (4H450). IL-17F (Interleukin 17F, CTLA-8)) is a cytokine belonging to the IL-17 family that is produced by inflammatory cells such as activated T cells, mast cells, and basophils. IL-17F is involved in allergic airway inflammation, and can induce several cytokines, chemokines, and adhesion molecules in bronchial epithelial cells, vein endothelial cells, fibroblasts, and eosinophils. IL-17F may be secreted as a homodimer, or a heterodimer with IL17A. It acts by binding to the type I receptor, IL-17R, aiding recruitment of monocytes and neutrophils at the site of inflammation by increasing chemokine production. IL-17F also stimulates induction of other pro-inflammatory cytokines TNF alpha, IL-1 beta, IL-6, and IL-8, |
Immunogen | n/a |
Other Names | CANDF6, IL-17F, ML-1, ML1, IL-24, cytokine ML-1, interleukin-17F, interleukin-24, mutant IL-17F |
Gene, Accession # | Entrez: 112744; Uniprot: Q96PD4 |
Catalog # | MA5-16228 |
Price | |
Order / More Info | IL-17F Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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