产品详情 |
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Antigenic Specificity | NSUN2 |
Clone | 3HCLC |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunofluorescence: 2 µg/mL, Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NSUN2 Antibody (3HCLC), ABfinity™ Rabbit Oligoclonal. NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA). Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Mutations of NSUN2 result in autosomal recessive 5 mental retardation (MRT5). |
Immunogen | n/a |
Other Names | tRNA (cytosine(34)-C(5))-methyltransferase |
Gene, Accession # | Entrez: 54888; Uniprot: Q08J23 |
Catalog # | 711068 |
Price | |
Order / More Info | NSUN2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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