产品详情 |
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Antigenic Specificity | BAP31 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunohistochemistry: 2 µg/mL, Western Blot: 0.5-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BAP31 Polyclonal Antibody. Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18. It may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria. Bap31 itself contains two caspase cleavage sites and is cleaved during apoptos |
Immunogen | n/a |
Other Names | 6C6-AG, BAP31, CDM, DXS1357E; 6C6-AG tumor-associated antigen; BCR-associated protein Bap31; p28 Bap31 |
Gene, Accession # | Entrez: 10134, 27061, 293852; Uniprot: P51572, Q61335 |
Catalog # | PA5-20194 |
Price | |
Order / More Info | BAP31 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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