产品名称 MHC Class II (I-A) Antibody from INVITROGEN ANTIBODIES
产品货号 12-5322-81
产品价格 现货询价,电话:010-67529703
产品规格 50 µg
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityMHC Class II (I-A)
CloneNIMR-4
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2b
Formatphycoerythrin (PE) conjugate
Size50 µg
Concentrationn/a
ApplicationsFlow Cytometry: 0.25 µg/test
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionMHC Class II (I-A) Monoclonal Antibody (NIMR-4), PE, eBioscience™. MHC class II molecules are heterodimers of non-covalently associated alpha (31-34 kDa) and beta (26-29 kDa) chains. Major histocompatibility complex class II antigen presentation requires the participation of lysosomal proteases in two convergent processes. First, the antigens endocytosed by the antigen presenting cells must be broken down into antigenic peptides. Second, class II molecules are synthesized with their peptide-binding site blocked by invariant chain (Ii), and they aquire the capacity to bind antigens only after Ii has been degraded in the compartments where peptides reside. MHC class II molecules present exogenously derived antigen to CD4+ T lymphocytes,
Immunogenn/a
Other Namesn/a
Gene, Accession #Entrez: 14961; Uniprot: P06342
Catalog #12-5322-81
Price
Order / More InfoMHC Class II (I-A) Antibody from INVITROGEN ANTIBODIES
Product Specific ReferencesPubMed: 22273745, 24145513, 24384074, 25289030, 25901937, 26265369, 26594606, 26998006, 27064280, 27374313, 29022922, 29482598, 29610255
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