产品详情 |
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Antigenic Specificity | CD117 (c-kit) |
Clone | 2B8 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b, κ |
Format | PE-Cy7 conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE/Cy7 anti-mouse CD117 (c-kit). CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells. |
Immunogen | Mouse bone marrow mast cells |
Other Names | c-KIT, Stem Cell Factor Receptor (SCFR) |
Gene, Accession # | Gene ID: 16590 |
Catalog # | 105813 |
Price | |
Order / More Info | CD117 (c-kit) Antibody from BIOLEGEND |
Product Specific References | PubMed: 16709810,18424727,20512127 |
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