| 产品详情 |
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| Antigenic Specificity | CD178 (Fas-L) |
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| Clone | NOK-1 |
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| Host Species | Mouse |
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| Reactive Species | human, baboon |
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| Isotype | IgG1, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), ICC, Immunofluorescence Microscopy (IF), IP, Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human CD178 (Fas-L). CD178 is a 38-42 kD type II glycoprotein also known as Fas ligand and CD95L. CD178 belongs to the TNF superfamily and is expressed on activated T lymphocytes, NK cells, monocytes, and granulocytes. CD178 is also expressed on parenchymal cells of the retina and cornea, retinal pigment epithelial cells, and testis. The extracellular region of FasL can be cleaved by matrix metalloproteinases (MMPs) to give rise to a 26 kD soluble protein. CD178 binds to CD95, a member of the TNFR superfamily, to induce apoptosis. CD95/CD95L interactions play an important role in the maintenance of peripheral tolerance and survival. |
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| Immunogen | L5178Y mouse T lymphoma cells expressing recombinant human FasL |
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| Other Names | Fas Ligand (FasL), CD95L, TNFSF6 |
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| Gene, Accession # | Gene ID: 356 |
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| Catalog # | 306402 |
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| Price | |
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| Order / More Info | CD178 (Fas-L) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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