产品名称 PF-562271 besylate from BIOVISION, INC.
产品货号 B1253-5
产品价格 现货询价,电话:010-67529703
产品规格 5 mg
产品品牌 BIOVISION, INC.
产品概述
产品详情
Edit&nbsp
Product NamePF-562271 besylate
DescriptionF-562271 is an ATP-competitive, reversible inhibitor of FAK (IC50 = 1.5 nM). It displays 10-fold reduced potency for PYK2 (IC50 = 14 nM) and >100-fold selectivity against other protein kinases. PF-562271 inhibits FAK phosphorylation with an EC50 value of 93 ng/ml in glioblastoma-bearing mice and has been shown to regress tumors in multiple xenograft models. MW: 665.66. Purity ≥98% by HPLC
Size5 mg
Concentrationn/a
Applicationsn/a
Other NamesN-[3-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl-methanesulfonamide, monobenzenesulfonate
Gene, Accession, CAS #CAS: 939791-38-5
Catalog #B1253-5
Price
Order / More InfoPF-562271 besylate from BIOVISION, INC.
Product Specific Referencesn/a
产品资料