| 产品详情 |
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| Product Name | ITF 2357 |
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| Description | Inhibits maize HDACs: HD2, HD-1B, and HD-1A (IC50s = 7.5-16 nM) and reduces TNFα, IL-1α, and IL-1β production (IC50s = 10-22 nM); inhibits activity of cells expressing JAK2V617F (IC50s = 1-10 nM), which are implicated in the pathophysiology of many myeloproliferative diseases |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 497833-27-9 givinostat histones deacetylases HDACs inhibitors inhibits inhibition pro-inflammatory cytokines janus kinases 2 JAK2 myeloproliferative diseases antitumor antiinflammatory anti-inflammatory anti inflammatory proinflammatory pro inflammatory HD2 HD-1B HD1A HD1B HD1A HD 1B HD 1A TNFα IL-1α IL-1β cytokines tumors necrosis factors interleukins cells JAK2V617F enzymes polycythaemia vera ITF-2357 ITF2357 |
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| Gene, Accession, CAS # | CAS: 732302-99-7 |
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| Catalog # | 11045-1 |
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| Price | |
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| Order / More Info | ITF 2357 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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