| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Phospho-CCR5(Ser349) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | affinity purified |
|---|
| Size | 100 µl |
|---|
| Concentration | 1mg/ml |
|---|
| Applications | Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blotting, ELISA |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Polyclonal antibody to detect Phospho-CCR5(Ser349). CCR5 a 7-transmembrane G-linked receptor for a number of inflammatory C-C type chemokines including MIP-1-alpha, MIP-1-beta and RANTES. Transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (along with CD4) for HIV-1 R5 isolates. Interacts with PRAF2. Interacts with HIV-1 surface protein gp120. Efficient ligand binding to CCL3/MIP-1alpha and CCR4/MIP-1beta requires sulfation, Oglycosylation and sialic acid modifications. Glycosylation on S6 is required for efficient binding of CCL4. |
|---|
| Immunogen | A synthesized peptide derived from human CCR5 around the phosphorylation site of Sersine 349. |
|---|
| Other Names | AM4 7, C-C chemokine receptor type 5, CC CKR 5, CCR 5, CD 195, Chemokine receptor CCR5, CHEMR13, CKR 5, CMKBR 5, FLJ78003, HIV1 fusion coreceptor, IDDM22, MIP-1 alpha receptor |
|---|
| Gene, Accession # | Gene ID: 1234, Accession: P51681 |
|---|
| Catalog # | A1734-100 |
|---|
| Price | |
|---|
| Order / More Info | Phospho-CCR5(Ser349) Antibody from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|