| 产品详情 |
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| Antigenic Specificity | CD40 |
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| Clone | 5C3 |
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| Host Species | Mouse |
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| Reactive Species | human, cross-reactivity: baboon, chimpanzee, cynomolgus monkey, rhesus, squirrel monkey |
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| Isotype | IgG1, κ |
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| Format | Alexa Fluor® 647 conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Alexa Fluor® 647 anti-human CD40. CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis. |
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| Immunogen | n/a |
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| Other Names | BP50, TNFRSF5 |
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| Gene, Accession # | Gene ID: 958 |
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| Catalog # | 334312 |
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| Price | |
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| Order / More Info | CD40 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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