产品详情 |
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Antigenic Specificity | CD40 |
Clone | 3/23 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | Alexa Fluor® 647 conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alexa Fluor® 647 anti-mouse CD40. CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. |
Immunogen | Recombinant mouse CD40 protein |
Other Names | Bp50, TNFRSF5 |
Gene, Accession # | Gene ID: 21939 |
Catalog # | 124613 |
Price | |
Order / More Info | CD40 Antibody from BIOLEGEND |
Product Specific References | n/a |
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