产品详情 |
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Product Name | CEP-32496 |
Description | A potent inhibitor of B-RafV600E (Kd = 14 nM in an in vitro binding assay); blocks B-RafV600E-dependent phosphorylation of MEK in human melanoma A375 and colorectal cancer COLO 205 cells (IC50s = 78 and 60 nM, respectively); displays good oral bioavailability |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | CEP32496 mutation mutant BRaf B-Raf BRAFV600E BRAF-V600E A-375 Colo205 pMEK pERK p-MEK P-ERK Val-600 |
Gene, Accession, CAS # | CAS: 1188910-76-0 |
Catalog # | 18776-5 |
Price | |
Order / More Info | CEP-32496 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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