| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Caspase-8 (Active) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | affinity purified |
|---|
| Size | 30 µg |
|---|
| Concentration | 0.5 mg/ml |
|---|
| Applications | Western blot |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Caspase-8 (Active) Antibody. Caspase-8, a member of the caspase-family of proteases, plays a key role in mediating Fas (CD95) and TNF induced apoptosis. Caspase-8 is synthesized as inactive pro-enzyme and activation of the enzyme involves proteolytic cleavage that leads to the release of the active p18 and p10 subunits. Activated caspase-8 is able to cleave and activate downstream caspases, such as caspase-3, -6, -7 and a death agonist member of the Bcl-2/Bcl-xL family, Bid, leading to apoptosis. |
|---|
| Immunogen | Synthetic peptide corresponding to residues surrounding amino acid 392 of mouse caspase-8 |
|---|
| Other Names | CASP8 , MGC78473 , CASP-8, MACH, procaspase-8, MCH5, ALPS2B, FLICE, CAP4, EC 3.4.22.61 |
|---|
| Gene, Accession # | Gene ID: 12370, Accession: BC006737 |
|---|
| Catalog # | 3259-30T |
|---|
| Price | |
|---|
| Order / More Info | Caspase-8 (Active) Antibody from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|