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| Product Name | Recombinant Human CNTF (Animal-Free) |
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| Description | CNTF is a member of the four-helix bundle cytokine family and is structurally related to other family members such as IL-6, IL-11, and LIF. Binding of CNTF to its receptor CNTFRα triggers the association with the IL-6 receptor gp130 and the LIF receptor LIFRβ, followed by activating the JAK-STAT, the ERK, and the PI3K signaling pathways. CNTF was first identified as a neuroprotective factor that supported the survival of embryonic chick ciliary neurons. CNTF has been shown to regulate the differentiation and survival of a variety of neuronal cells and has been applied as the treatment for retinal degenerative diseases caused by genetic defect or damage induced by toxins, auto-antibodies, or strong light. CNTF is also revealed as a myotrophic factor for denervated skeletal muscle and a modulator for AMPK-mediated energy balance control. |
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| Size | 20 µg |
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| Concentration | n/a |
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| Applications | BA |
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| Other Names | Ciliary neurotrophic factor |
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| Gene, Accession, CAS # | Gene ID: 1270 |
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| Catalog # | 710104 |
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| Order / More Info | Recombinant Human CNTF (Animal-Free) from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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