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Product Name | Rat IL-17A ELISA |
Description | IL-17A, a homodimeric cytokine of about 32 kDa, is largely produced by activated memory T lymphocytes, but stimulates innate immunity and host defense. IL-17A and IL-17F both mobilize neutrophils partly through granulopoeisis and CXC chemokine induction, as well as increased survival locally. IL-17A and IL-17F production by T lymphocytes is regulated by IL-23 independent of T cell receptor activation. The Th1 and Th2 cell classification has until recently provided the framework for understanding CD4+ T cell biology and the interplay between innate and adaptive immunity. The Th17 lineage produces interleukin 17, which is highly proinflammatory and induces severe autoimmunity. Increased levels of IL-17 have been associated with several conditions, including airway inflammation, rheumatoid arthritis, intraperitoneal abscesses and adhesions, inflammatory bowel disease, allograft rejection, psoriasis, cancer and multiple sclerosis. Sample Types: cell culture, citrate plasma, EDTA plasma, heparin plasma, serum. Sample Size: 50 µL. Range: 1.6 - 100 pg/mL. Sensitivity: 1.0 pg/mL. Time: 3hr 30min |
Size | 96 wells |
Concentration | n/a |
Applications | Immunoassays. Research Use Only. Not for Use in Diagnostic Procedures. |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | 61-ILART-E01 |
Price | |
Order / More Info | Rat IL-17A ELISA from ALPCO |
Product Specific References | n/a |
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