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Product Name | Manumycin A |
Description | An antibiotic Isolated from Streptomyces parvulus. A Potent, selective and competitive cell permeable rasfarnesyltransferase (FTase) inhibitor (IC50 = 30 nM). Does not affect geranylgeranyltransferase (GGTase) (IC50 = 180 µM). Blocks insulin-induced MAP kinase activation in rat cardiac myocytes (19 µM).µM). Inhibition is competitive with respect to farnesyl pyrophosphate and non-competitive with respect to Ras. MW: 550.64. Purity ≥96% by HPLC |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | NSC-622141; UFC 1C |
Gene, Accession, CAS # | CAS: 52665-74-4 |
Catalog # | 2333-5 |
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Order / More Info | Manumycin A from BIOVISION, INC. |
Product Specific References | n/a |
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