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Product Name | BMS-986158 |
Description | BMS-986158 is a potent bromodomain (BRD) and extra-terminal domain (BET) family inhibitor. BMS-986158 binds to the acetyl-lysine binding site in the BRD of BET proteins, thereby preventing the interaction between BET proteins and acetylated histones. This disrupts chromatin remodeling and prevents the expression of certain growth-promoting genes, resulting in an inhibition of tumor cell growth. MW: 495.63. Purity ≥98% by HPLC |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (S)-2-(3-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-5-(phenyl(tetrahydro-2H-pyran-4-yl)methyl)-5H-pyrido[3,2-b]indol-7-yl)propan-2-ol |
Gene, Accession, CAS # | CAS: 1800340-40-2 |
Catalog # | B2021-1 |
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Order / More Info | BMS-986158 from BIOVISION, INC. |
Product Specific References | n/a |
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