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Product Name | EED-226 |
Description | EED-226 is a potent, selective, allosteric Polycomb repressive complex 2 (PRC2) inhibitor (IC50 = 23.4 nM). EED-226 binds to the H3K27me3 binding pocket of EED (Embryonic Ectoderm Development) to allosterically inhibit PRC2. EED-226 induces robust and sustained tumor regression in EZH2MUT preclinical DLBCL model. MW: 369.4. Purity ≥98% by HPLC |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-(Furan-2-ylmethyl)-8-(4-(methylsulfonyl)phenyl)[1,2,4]-triazolo[4,3-c]pyrimidin-5-amine |
Gene, Accession, CAS # | CAS: 2083627-02-3 |
Catalog # | B1845-25 |
Price | |
Order / More Info | EED-226 from BIOVISION, INC. |
Product Specific References | n/a |
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