| 产品详情 |
| Edit |   |
|---|
| Product Name | Cathepsin B (CTSB) BioAssay™ ELISA Kit (Mouse) |
|---|
| Description | Sandwich ELISA quantitative detection kit for Mouse Cathepsin B in cell culture supernates, serum and plasma (heparin, EDTA). Cathepsin B is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSB gene.1, 2 And this gene is mapped to chromosome 8p22.3 The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. Cathepsin B was once suspected as a candidate protease participating in the conversion of β-amyloid precursor protein into the amyloid plaques found in Alzheimer's disease patients. However, this function is now known to be mediated by BACE1 protease. It is now thought that cathepsin B can degrade β-amyloid precursor protein into harmless fragments. Thus, it is conceivable cathepsin B may play a pivotal role in the natural defense against Alzheimer's disease.4 Ov |
|---|
| Size | 96 tests |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | Gene ID: 13030, SwissProt: P10605 |
|---|
| Catalog # | 143740 |
|---|
| Price | |
|---|
| Order / More Info | Cathepsin B (CTSB) BioAssay™ ELISA Kit (Mouse) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|