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| Product Name | HDAC4, Recombinant, Human, aa1-227, GST-Tag (Histone Deacetylase 4) |
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| Description | Purity ~90% (SDS-PAGE). Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Source: Recombinant protein corresponding to aa1-227 from human Histone Deacetylase 4, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~53.7kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P56524 |
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| Catalog # | 373602 |
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| Order / More Info | HDAC4, Recombinant, Human, aa1-227, GST-Tag (Histone Deacetylase 4) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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