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| Product Name | HDAC7, Recombinant, Human, aa645-915, His-Tag (Histone Deacetylase 7) |
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| Description | Purity ~90% (SDS-PAGE). Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3. Source: Recombinant protein corresponding to aa645-915 from human Histone Deacetylase 7, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~33.1kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Histone deacetylase 7A, HD7a |
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| Gene, Accession, CAS # | SwissProt: Q8WUI4 |
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| Catalog # | 373605 |
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| Order / More Info | HDAC7, Recombinant, Human, aa645-915, His-Tag (Histone Deacetylase 7) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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