| 产品详情 |
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| Product Name | Cedrulatinib |
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| Description | Cerdulatinib is a novel, dual spleen tyrosine kinase (Syk) and janus kinase (JAK) inhibitor. It preferentially inhibits JAK1 and JAK3 dependent cytokine mediated signaling and functional responses in various cell types. IL2 mediated STAT5 Y694 is inhibited with an IC50 of 0.27 µM, while IL4 mediated signaling to STAT6 Y641 and functional responses in B cells and monocytes, namely CD69, CD25, and CD23 up-regulation, are inhibited with IC50's within the range of 0.11 µM to 0.57 µM. MW: 445.54. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-(cyclopropylamino)-2-((4-(4-(ethylsulfonyl)piperazin-1-yl)phenyl)amino)pyrimidine-5-carboxamide; PRT2070; PRT-2070; PRT 2070; PRT-062070; PRT 062070; PRT062070. |
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| Gene, Accession, CAS # | CAS: 1198300-79-6 |
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| Catalog # | 2803-5 |
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| Price | |
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| Order / More Info | Cedrulatinib from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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