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| Product Name | IL-28, human recombinant |
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| Description | IL-28A is distantly related to type I interferons and the IL-10 family. Expression of IL-28A is induced by viral infection which interacts with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, β (IL10RB) and interleukin 28 receptor α. IL-28A exhibits common features with type I IFNs such as antiviral activity, antiproliferative activity and in vivo antitumour activity. IL-28A acts similarly to IFNs, but is less effective generally and has activity in a more limited range of cell lines. IL-28A induces ELR(-) CXC chemokine mRNA in human peripheral blood mononuclear cells, in an IFN-γ-independent manner. IL-28A produced in response to viral infection, activates both monocytes and macrophages |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Interleukin-28A, IL-28A, IFN-Lambda 2, Interferon-Lambda 2, Cytokine ZCYTO20, IL28A, IFNL2, ZCYTO20, Cytokine receptor family 2 member 12. |
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| Gene, Accession, CAS # | IL28, Gene ID: 282616, Accession: Q8IZJ0 |
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| Catalog # | 4978-1000 |
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| Price | |
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| Order / More Info | IL-28, human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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