| 产品详情 |
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| Product Name | MMAE |
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| Description | MMAE (Monomethyl auristatin E) is a synthetic derivative of dolastatin 10 that functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. Suppresses tumor cell viability in vitro (GIC50 values are 0.22, 0.49 and 0.54 nM in BT474, MDA-MB-361-DYT2 and N87 cells, respectively). It is commonly conjugated with monoclonal antibodies directed at antigens specific to cancer cells for tumor-directed cytotoxicity. MW: 717.98. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-Methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide,Monomethyl auristatin E |
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| Gene, Accession, CAS # | CAS: 474645-27-7 |
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| Catalog # | B2344-5 |
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| Price | |
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| Order / More Info | MMAE from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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