| 产品详情 |
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| Antigenic Specificity | CD45 |
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| Clone | OX-1 |
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| Host Species | Mouse |
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| Reactive Species | rat |
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| Isotype | IgG1, κ |
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| Format | biotin conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), IHC, Immunofluorescence Microscopy (IF) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Biotin anti-rat CD45. CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro. |
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| Immunogen | Enriched glycoprotein fraction from Wistar rat thymocytes |
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| Other Names | LCA, T200, B220, Ly-5 |
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| Gene, Accession # | Gene ID: 24699 |
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| Catalog # | 202203 |
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| Price | |
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| Order / More Info | CD45 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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