| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD45 |
|---|
| Clone | 2D1 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1, κ |
|---|
| Format | Brilliant Violet 421™ conjugate |
|---|
| Size | 100 tests |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry (FC) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Brilliant Violet 421™ anti-human CD45. CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. |
|---|
| Immunogen | Human PBMC |
|---|
| Other Names | Leukocyte Common Antigen (LCA), T200 |
|---|
| Gene, Accession # | Gene ID: 5788 |
|---|
| Catalog # | 368522 |
|---|
| Price | |
|---|
| Order / More Info | CD45 Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|